WARNING: This product is for research use only, not for human or veterinary use. Vardenafil, also known as BAY 38-9456, is a PDE5 inhibitor used for treating erectile dysfunction. Vardenafil's indications and contra-indications are the same as with other PDE5 inhibitors; it is closely related in function to sildenafil citrate (Viagra) and tadalafil (Cialis). The difference between the vardenafil molecule and sildenafil citrate is a nitrogen atom's position and the change of sildenafil's piperazine ring methyl group to an ethyl group. Tadalafil is structurally different from both sildenafil and vardenafil.
| Aspect | Description | Typical Dosage | Onset Time | Duration of Action |
|---|---|---|---|---|
| Vardenafil 5 mg | A medication used to treat erectile dysfunction | 5 mg | 30-60 min | Up to 4-5 hours |
| Pharmacological Class | Phosphodiesterase type 5 inhibitor | N/A | N/A | N/A |
| Brand Names | Levitra, Staxyn (dissolvable film) | N/A | N/A | N/A |
Vardenafil's relatively short effective time is comparable to but somewhat longer than sildenafil's. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). This drug may be formulated in DMSO 0 - 4 C for short term (days to weeks), or -20 C for long term (months). Related CAS# CAS#224789-15-5 (Vardenafil dihydrochloride); CAS#224785-90-4 (Vardenafil free base).
| Side Effect | Frequency | Severity | Management Tips |
|---|---|---|---|
| Headache | Common | Mild to Moderate | Hydration, OTC pain relief |
| Flushing | Frequently reported | Mild | Cool environment, calming techniques |
| Nasal congestion | Sometimes | Mild | Decongestants (if advised) |
| Dizziness | Occasionally | Mild | Sit or lie down, avoid driving |
| Upset stomach | Less common | Mild | Take with food, monitor symptoms |
CAS#330808-88-3 (Vardenafil hydrochloride trihydrate) The following data is based on the product molecular weight 561.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
[Modernity in the treatment of erectile dysfunction: Levitra (vardenafil) in the form of oral dispersible tablet]. 2013 May-Jun;(3):102-4, 106.
COGR represents over 230 of the most research-intensive institutions in the U.S., providing expert policy advocacy and a strong voice on the financial and regulatory issues that impact research. Members gain access to timely insights, collaboration opportunities, and a national community of research leaders. COGR surveys its member institutions throughout the year to gather essential data and insights on topics of particular interest to the academic research community, which helps to support COGR’s advocacy efforts. In addition to these policy topic surveys, COGR also has a Volunteer Survey, open year round, so that representatives from member institutions can note their areas of expertise and their interest in engaging in various volunteer opportunities with COGR. If you have any questions about an open survey, please contact memberservices@. Review. 3: Venhuis BJ, de Kaste D. Towards a decade of detecting new analogues of sildenafil, tadalafil and vardenafil in food supplements: a history, analytical aspects and health risks. A state of art review on vardenafil in men with erectile dysfunction and 100 sex tablet associated underlying diseases. [Vardenafil for refractory erectile dysfunction: the latest advances]. 2009 Nov;15(11):1035-8.
| Product | Dosage | Quantity + Bonus | Price | |
|---|---|---|---|---|
| Cialis Generic | 60mg | 10 Pills | 41.22€ 39.26€ | |
| Kamagra Oral Jelly | 100mg | 220 + 18 Sachets | 662.24€ 630.70€ | |
| Viagra Soft Tabs | 100mg | 270 + 10 Pills | 419.95€ 399.95€ | |
| Kamagra Soft Tabs | 100 mg | 84 + 4 Pills | 233.05€ 221.95€ | |
| Kamagra Polo | 100 mg | 20 Pills | 83.56€ 79.58€ | |
| Levitra Original | 20mg | 12 Pills | 81.99€ 78.09€ | |
| Kamagra Polo | 100mg | 120 + 6 Pills | 327.15€ 311.57€ | |
| Cialis Original | 20mg | 48 + 4 Pills | 224.69€ 213.99€ | |
| Levitra Original | 20mg | 14 + 2 Pills | 102.27€ 97.40€ | |
| Cialis Black | 80mg | 90 + 6 Pills | 207.88€ 197.98€ | |
| Viagra Professional | 100mg | 10 Pills | 44.09€ 41.99€ | |
| Kamagra Oral Jelly | 100mg | 110 + 9 Sachets | 334.87€ 318.92€ | |
| Cialis Soft Tabs | 20mg | 20 + 2 Pills | 66.98€ 63.79€ | |
| Levitra Soft Tabs | 20mg | 180 + 10 Pills | 398.14€ 379.18€ | |
| Kamagra Polo | 100mg | 12 Pills | 60.21€ 57.34€ |
Review. 7: Morales AM, Mirone V, Dean J, Costa P. Vardenafil for the treatment of erectile dysfunction: an overview of the clinical evidence. 9: Mirone V, creams for erectile dysfunction Fusco F, Rossi A, Sicuteri R, Montorsi F. Tadalafil and vardenafil vs sildenafil: a review of patient-preference studies. Global experiences with vardenafil in men with erectile dysfunction and underlying conditions. Vardenafil: a selective inhibitor of phosphodiesterase-5 for the treatment of erectile dysfunction. 2007 May;8(7):965-74. Review. 12: Doggrell S. Do vardenafil and tadalafil have advantages over sildenafil in the treatment of erectile dysfunction? 13: Hong K, Jiang H. [Safety and tolerability of Vardenafil]. 2006 Sep;12(9):857-60. Review. 14: Sommer F. Potency and selectivity of vardenafil: a phosphodiesterase Type 5 inhibitor. 2005 Aug;1(2):295-301. Review. 15: Montorsi F, Salonia A, Briganti A, Barbieri L, Zanni G, Suardi N, Cestari A, Montorsi P, Rigatti P.
Vardenafil for the treatment of erectile dysfunction: a critical review of the literature based on personal clinical experience. Comparison of clinical trials with sildenafil, vardenafil and tadalafil in erectile dysfunction. 2005 Jan;6(1):75-84.
Learn about the most common sexual conditions affecting men and women. Sexual health information including birth control, impotence, herpes, sexually transmitted diseases, staying healthy, women's sexual health concerns, and men's sexual health concerns. Peyronie's Disease (Curvature of the Penis)Peyronie's disease or curvature of the penis (Peyronie disease) is a condition in which scar tissue develops inside the penis. This scar tissue causes the penis to develop an abnormal curvature in the scarred area. At this time, there is no known cause of Peyronie's disease.
Symptoms of Peyronie's disease include pain during intercourse or ejaculation, erectile dysfunction (ED, impotence), the inability to have sexual intercourse, anxiety, stress, an indentation of the shaft at the site where there is plaque or scarring, and an angulation of the penis when erect or flaccid. There is no cure for Peyronie's disease, however, there are medications that can reduce symptoms of the disease. Surgery or penile implants may be an option for severe cases. Peyronie's disease or curvature of the penis (Peyronie disease) is a condition in which scar tissue develops inside the penis. Diabetic NeuropathyDiabetic neuropathy is a condition in which nerve damage has occurred as a complication of diabetes. Review.
Men's health is an important component to a happy lifestyle and healthy relationships. 8 Natural Remedies for Erectile Dysfunction (ED) Effective Erectile Dysfunction Treatments: What to Do After an Impotence Diagnosis Things You Should Know About the Penis Generic Drugs, Are They as Good as Brand-Names? You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. Check live price on Amazon.co.uk Check availability and price on eBay.co.uk.
Yorkshire.com may be paid for purchases made through this link, by eBay Partner Network. Vardenafil is a safe and reliable erectile dysfunction treatment recommended for diabetic individuals. Browse their full range on Yorkshire.com Draper D20 20V Ash Vacuum Cleaner with Battery and Charger Draper Crevice Nozzle for VC1600 and VC2000B Vacuums SIP 1/2 Inch Composite Air Impact Wrench Tutti Bambini Jonah Rocking Chair and Foot Stool - Pebble Draper Extension Tube for WDV10, WDV15A, WDV20ASS COGR also signed on to a broader research community letter led by ACE raising similar concerns. COGR provides this compilation of resources, many developed by COGR, explaining Facilities and Administrative (F&A/Indirect) costs, the importance of these… COGR brings together the nation’s top research institutions to advocate for sound policies, streamline compliance, and strengthen the U.S. research enterprise. 17: Huang YR. [Vardenafil for the treatment of men with erectile dysfunction after radical retropubic prostatectomy].
2005 Jan;11(1):76-9. Review.
The pain from the nerve damage can be severe with tingling or numbness in the part of the body affected. Diabetic neuropathy can occur anywhere in the body. Diabetic neuropathy can cause symptoms like intense pain, numbness, burning, or tingling in the part of the body affected by the condition. There are four types of neuropathy, which include peripheral, autonomic, proximal, and focal. Natural therapies and medications may help relieve the pain and other symptoms of diabetic neuropathy.
Diabetic neuropathy is a condition in which nerve damage has occurred as a complication of diabetes. Can Erectile Dysfunction Become Permanent?Erectile dysfunction (ED) is the medical term for impotence. Treatments for erectile dysfunction include lifestyle changes, psychotherapy, medications, devices, and surgery. Erectile dysfunction (ED) is the medical term for impotence. What Is the Fastest Way To Cure Erectile Dysfunction?Learn about the symptoms of erectile dysfunction, treatment options, and the quickest way to help you resolve the condition. 18: Eardley I.
It is more likely that you'll develop erectile dysfunction as you get older, but aging itself does not cause erectile dysfunction. Many factors can cause erectile dysfunction, including those that affect your endocrine, vascular, and nervous systems. What is erectile dysfunction, and what are the signs and symptoms? Learn about the risks and causes of erectile dysfunction and what treatments are available for erectile dysfunction. Learn about the symptoms of erectile dysfunction, treatment options, and the quickest way to help you resolve the condition.
Is Erectile Dysfunction Permanent?Erectile dysfunction (ED) occurs when you have trouble getting or maintaining an erection on a regular basis. Erectile dysfunction is treated with lifestyle, behavioral, medical, and surgical interventions. Erectile dysfunction (ED) occurs lovegra 100 mg when you have trouble getting or maintaining an erection on a regular basis. Men's HealthMen's health is an important component to a happy lifestyle and healthy relationships. Eating healthy, exercise, managing stress, and knowing when to have medical tests for a particular age is key to disease prevention in men. Vardenafil: a new oral treatment for erectile dysfunction. 2004 Aug;58(8):801-6. Review. 19: Markou S, Perimenis P, Gyftopoulos K, Athanasopoulos A, Barbalias G. Vardenafil (Levitra) for erectile dysfunction: a systematic review and meta-analysis of clinical trial reports. 2004 Dec;16(6):470-8.
Review.
| Interacting Drug | Effect on Vardenafil 5 mg | Recommendations |
|---|---|---|
| Nitrates | Severe hypotension risk | Avoid concurrent use |
| CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) | Increased Vardenafil levels | Reduce dose or avoid |
| Alpha-blockers | Potential for hypotension | Use with caution, monitor blood pressure |
| Grapefruit juice | Increases drug plasma concentration | Limit intake before dosing |
20: Bischoff E. Vardenafil preclinical trial data: potency, pharmacodynamics, pharmacokinetics, and adverse events. 10 mg PO ~1 hour before sexual activity; may be increased to 20 mg or reduced to 5 mg, depending on effectiveness and tolerance; not to exceed 1 dose/day TabletKetoconazole 200 mg/day or itraconazole 200 mg/day: Vardenafil dosage not to exceed 5 mg/dayIndinavir, saquinavir, atazanavir, clarithromycin, ketoconazole 400 mg/day or itraconazole 400 mg/day: Vardenafil dosage not to exceed 2.5 mg/dayRitonavir (600 mg q12hr) or cobicistat: Vardenafil dosage not to exceed 2.5 mg/72 hrErythromycin 500 mg q8hr: Vardenafil dosage not to exceed 5 mg/day Ketoconazole 200 mg/day or itraconazole 200 mg/day: Vardenafil dosage not to exceed 5 mg/day Indinavir, saquinavir, atazanavir, clarithromycin, ketoconazole 400 mg/day or itraconazole 400 mg/day: Vardenafil dosage not to exceed 2.5 mg/day Ritonavir (600 mg q12hr) or cobicistat: Vardenafil dosage not to exceed 2.5 mg/72 hr Erythromycin 500 mg q8hr: Vardenafil dosage not to exceed 5 mg/day Oral disintegrating tablet (ODT)Strong or moderate CYP3A4 inhibitors: Do not use (unable to adjust vardenafil dose) Strong or moderate CYP3A4 inhibitors: Do not use (unable to adjust vardenafil dose) Only initiate vardenafil if stabilized on alpha-blocker Stabilized on alpha-blocker therapy (eg, alfuzosin, terazosin, tamsulosin): 5 mg/day PO initially Stabilized on alpha-blocker therapy and taking moderate-to-strong CYP3A4 inhibitor: 2.5 mg/day PO initially Consider time interval between dosing when vardenafil is concomitantly used with alpha-blocker therapy Mild-to-severe: No dosage adjustment necessary Mild (Child-Pugh A): No dosage adjustment necessary Moderate (Child-Pugh B): Start 5mg PO ~1 hr before sexual activity; not to exceed 10 mg once daily Severe (Child-Pugh C): Do not use Mild (Child-Pugh A): No dosage adjustment necessary Moderate-to-severe (Child-Pugh B or C): Do not use Orphan designation for treatment of pulmonary arterial hypertension Respira Therapeutics, Inc; 5901 Indian School Road NE, suite 107; Albuquerque, New Mexico 87110 Film-coated tablet: 10 mg PO ~1 hour before sexual activity; may be increased to 20 mg or reduced to 5 mg, depending on effectiveness and tolerance; not to exceed 1 dose/day Orally disintegrating tablet (ODT): 10 mg PO placed on tongue ~1 hour before sexual activity; not to exceed 1 dose/day; not interchangeable with 10-mg film-coated tablet; if higher or lower doses required, film-coated tablet should be prescribed AUC and Cmax increased by 39% and 21%, respectively, in elderly men (compared with men <45 years) lefamulinlefamulin will increase the level or effect of vardenafil by affecting hepatic/intestinal enzyme CYP3A4 metabolism.